Arsenal: David Ospina's ankle injury means that Petr Cech will line up in goal once again, whilst Henrikh Mkhitaryan will play no part after being ruled out until the end of the season with a knee injury. Santi Cazorla remains sidelined with his achilles problem, whilst utility man Ainsley Maitland-Niles is a doubt with a knock. Granit Xhaka is sidelined with a bout of flu.
CSKA Moscow: Right-back Mario Fernandes won't feature due to a thigh problem, whilst centre-back Viktor Vasin is out long term aftear tearing his ACL.
Arsenal boss Arsene Wenger:
"Milan is a good example for us to have a similar attitude.
"We have to overcome not just protecting what we have built, but have a similar attitude to Milan and have a positive attitude early on.
"It’s very important we have a positive start tomorrow."
CSKA Moscow boss Viktor Goncharenko:
"Roma played a magnificent match and made a miracle. We don't have a lot of chances to repeat the same miracle, but sometimes miracles happen in football. Of course Arsenal are extremely motivated because winning the Europa League is the way into the Champions League, so this is their motivation.
"Arsenal have a philosophy and have stuck to it for a long time, for many years, regardless of their record.
"If they are losing or winning they still play to make supporters and fans happy. When you act like this, trying to cheer up the supporters, you can have some problems in the defence.
"Tomorrow's strategy for Arsenal could be done in different ways, but they will be focusing on their attack of course.
"If we play without believing in yourself and without faith it is better not to play at all. We need to go to the pitch believing in ourselves and that we can make it into the next round.
"We need to change some things, but it is not guaranteed that we will succeed or fail, so will implement some alterations then see how it happens."
Did you know?
CSKA faced Arsenal twice in the Champions League in 2006/07, winning the first game 1-0 and claiming a goalless draw in the second.
The Russians have already lost to English opposition this season, being thumped 4-1 by Manchester United in the Champions League Group Stage.
Form:
Possible lineups:
CSKA Moscow: Akinfeev; V. Berezutski, S.Ignashevich, A. Berezutski; Kuchaev, Natkho, Golovin, Schenikov; Dzagoev, Musa; Wernbloom.
Arsenal: Cech; Bellerin, Koscielny, Mustafi, Monreal; Elneny, Wilshere, Ramsey; Ozil, Lacazette, Welbeck.